Targeting MARCO can lead to enhanced dendritic cell motility and anti-melanoma activity
نویسندگان
چکیده
منابع مشابه
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We have reported the upregulation of MARCO, a member of the class A scavenger receptor family, on the surface of murine and human dendritic cells (DCs) pulsed with tumor lysates. Exposure of murine tumor lysate-pulsed DCs to an anti-MARCO antibody led to loss of dendritic-like processes and enhanced migratory capacity. In this study, we have further examined the biological and therapeutic impli...
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ژورنال
عنوان ژورنال: Cancer Immunology, Immunotherapy
سال: 2010
ISSN: 0340-7004,1432-0851
DOI: 10.1007/s00262-009-0813-5